Humanity is in great danger as four different pandemics threaten the Earth. Players take on the roles of highly skilled members of a disease control team to combat these outbreaks. They travel around the world to contain the infection risks while also laying the groundwork for researching cures. Everyone must contribute their unique strengths to defeat the diseases. In this cooperative game hit, which was nominated for the Game of the Year award in 2009, all players either win or lose together. Various difficulty levels also maintain the high replay value over the long term.